Curriculum VitaeTobias Dörr
Postdoc, Harvard Medical School (since 2011)
PhD (Biology), Northeastern University (2011)
e-mail: firstname.lastname@example.org ( jwdtobi null@null gmail NULL.com)
Research area:I am generally interested in adaptive bacterial stress pathways and their implications in resistance/tolerance to antibiotics. At the moment, I am working on the mechanism of stationary-phase specific peptidoglycan remodeling in Vibrio cholerae and how this process affects survival after exposure to environmental stresses.
Dörr, T, Alvarez, L, Delgado, F, Davis, BM, Cava, F and Waldor, MK: A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta lactam tolerance, PNAS (in press)
Dörr, T, Davis, BM and Waldor MK (2015): Endopeptidase-mediated beta lactam tolerance, PLOS Pathogens
Möll A, Dörr T, Alvarez L, Davis BM, Cava F, Waldor MK. (2015) A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance, Environmental Microbiology
Möll A*, Dörr T*, Alvarez L, Chao MC, Davis BM, Cava F, Waldor MK. (2014) Cell separation in Vibrio cholerae is mediated by a single amidase whose action is modulated by two non-redundant activators, J Bac.
Dörr T, Lam H, Alvarez L, Cava F, Davis BM and Waldor MK (2014): A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae, PLOS Genetics.
Dörr T, Möll A, Chao MC, Cava F, Lam H, Davis BM, Waldor MK (2014): Differential requirement for PBP1a and PBP1b in the in vivo and in vitro fitness of Vibrio cholerae., Infect Immun.
Dörr T, Cava F, Lam H, Davis BM, Waldor MK (2013): Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae, Mol Microbiol.
Gurnev PA, Ortenberg R, Dörr T, Lewis K, Bezrukov SM (2012): Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers, FEBS Lett., 586(16):2529-34
Dörr T, Vulic M, Lewis K (2010): Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli, PloS Biology, 8(2):e1000317
Dörr T, Lewis K, Vulic M (2009): SOS response induces persistence to fluoroquinolones, PloS Genetics, 5(12): e1000760.